Description
Product Characteristics: D-amino acid oxidase activator antibody, DAOA antibody, DAOA_HUMAN antibody, G72 transcript antibody, LG72 antibody, Protein G72 antibody, Schizophrenia and bipolar disorder associated protein G72 antibody, SG72 antibody
Target Information: This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]